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Anti-inflammatory mechanisms: Reduced clinical signs (less injection, photophobia, pain)

Glyphosate exposure is associated with decreased beneficial microbes (e.g., Bifidobacteria), reduced aromatic amino acid synthesis (tryptophan, tyrosine, phenylalanine), increased oxidative stress, and astrocyte activation (elevated GFAP expression in animal models) [44]

Step 3: Extending the dataset with 2D descriptors The purpose of this step is extending the information space of compounds by adding basic topological and physico-chemical information

Real space refinement in Phenix (v 1.19.2) 43 was performed before manually fixing the clashes and outliers in Coot (v 0.9.8.92) 44